Uganda approves twice-yearly HIV prevention injection in major AIDS fight breakthroughs.

Uganda has approved the use of Lenacapavir, a twice-yearly HIV prevention injection, marking a major milestone in the country’s fight against HIV/AIDS.The bi-annual HIV pre-exposure prophylaxis (PrEP) injection, developed by US-based Gilead Sciences, provides a long-acting, highly effective alternative to daily oral medication.With just two injections per year, the drug, endorsed by the World Health Organisation (WHO) in July 2025 and prequalified in October, offers a convenient option for individuals who struggle with adherence, face stigma or have limited access to healthcare services. ROWAN is looking into this for our future care, although much research needs to be done in order to confirm this is the best way forward.